02153naa a2200217 a 450000100080000000500110000800800410001910000180006024501440007826000090022252014740023165000230170565000310172865000270175970000160178670000180180270000180182070000170183870000180185577300620187311353892025-01-06       2025    bl uuuu     u00u1 u    #d1 aBRILINGER, D.  aExploring Matrine and Oxymatrine as Potential Bioinsecticide to Control Drosophila suzukii (DipterabDrosophilidae).h[electronic resource]  c2025  aA bottleneck in sustainable fruit production is the replacement of chemical products with natural compounds. Matrine and  oxymatrine, derived from a Chinese medicinal herb, have exhibited potential for controlling agricultural pests. However,  there is no information regarding their efectiveness in managing dipterans. Thus, we carried out experiments to evaluate  the efect of the botanical compounds matrine and oxymatrine on Drosophila suzukii (Matsumura) adults under laboratory  conditions. First, we tested four doses of the commercial product matrine, with distilled water as a control treatment. Each  treatment was ofered as a droplet, to fve D. suzukii couples in screened cages. Adult mortality was evaluated at intervals  of 12, 24, 36, 48, 60, and 72 h post-exposure. All doses tested of the commercial matrine-based product caused up to 58%  of mortality in D. suzukii adults. Second, the consumption of pure extract of oxymatrine was evaluated using a CAFE assay.  Three D. suzukii females were exposed to oxymatrine concentrations of 0.05, 1.0, 2.5, 5.0, and 7.0% in a 20% sugar solution  for 24 h. Afterwards, the fies were deprived of food for 40 h, and mortality was evaluated. The pure extract of oxymatrine  induced mortality in D. suzukii females only at doses of 2.5, 5.0, and 7.0%. These botanical compounds demonstrate the  potential to be used to control D. suzukii adults and can be explored as one tool of the Integrated Management Program.  aBotanical compound  aIntegrated pest management  aQuinolizidine alkaloid1 aFIEDLER, M.1 aARIOLI, C. J.1 aWERNER, S. S.1 aWERTHEIM, B.1 aBOF, M. I. C.  tNeotropical Entomology, Vi??osa, MGgv. 54, p. 1-9, 2025.