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Registro Completo |
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Biblioteca(s): |
Epagri-Sede. |
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Data corrente: |
10/11/2021 |
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Data da última atualização: |
10/11/2021 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
LIMA, A. F.; RIBEIRO, L. P.; GONÇALVES, G. L. P.; MAIMONE, N. M.; GISSI, D. S.; LIRA, S. P.; VENDRAMIM, J. D. |
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Título: |
Searching for bioactive compounds from Solanaceae: lethal and sublethal toxicity to Spodoptera frugiperda and untargeted metabolomics approaches. |
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Ano de publicação: |
2021 |
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Fonte/Imprenta: |
Journal of Pest Science, Dordrecht, p. 1-13, 2021. |
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Idioma: |
Inglês |
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Conteúdo: |
The fall armyworm, Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae), is a major pest of maize crops and others
row crops on the American continent, and this pest has spread to Africa and Asia. Such lepidopteran pest presents resistant
populations to synthetic insecticides and to Bacillus thuringiensis (Bt) toxins and, consequently, new (bio) insecticides with
distinct modes of action are required. In order to search for derivatives from Solanaceae as a potential source of bioactive
compounds, a screening of 38 ethanolic extracts were prepared from 25 Solanaceae species. Using dietary exposure assessment,
the ethanolic extracts from leaves of Acnistus arborescens (L.) Schltdl. and Datura stramonium L. were the most
promising derivatives. A bioguided fractionation was performed with both plant species. The A. arborescens dichloromethane
fraction was the most active, causing sublethal (growth inhibition) and lethal toxicity. Thus, this fraction was submitted
to another fractionation procedure resulting in three subfractions (dichloromethane, ethyl acetate and methanol) that were
tested against S. frugiperda caterpillars. All subfractions lead to significant sublethal effects, however, without significant
mortality. The chemical diversity in the subfractions of A. arborescens was assessed through untargeted approaches, such
as molecular networking and the in silico annotation tool NAP, by which two withanolides glycosides were annotated:
(22R)-1-Oxo-3beta-(beta-D-glucopyranosyloxy)-14,20,22,27-tetrahydroxyergosta-5,24-diene-26-oic acid delta-lactone and
withanoside XI. Therefore, derivatives of Solanaceae present promising compounds that may be useful in the framework of
S. frugiperda integrated pest management. In addition, metabolomics is an innovative alternative and powerful approach to
facilitate the putative identification of compounds in studies of natural products. MenosThe fall armyworm, Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae), is a major pest of maize crops and others
row crops on the American continent, and this pest has spread to Africa and Asia. Such lepidopteran pest presents resistant
populations to synthetic insecticides and to Bacillus thuringiensis (Bt) toxins and, consequently, new (bio) insecticides with
distinct modes of action are required. In order to search for derivatives from Solanaceae as a potential source of bioactive
compounds, a screening of 38 ethanolic extracts were prepared from 25 Solanaceae species. Using dietary exposure assessment,
the ethanolic extracts from leaves of Acnistus arborescens (L.) Schltdl. and Datura stramonium L. were the most
promising derivatives. A bioguided fractionation was performed with both plant species. The A. arborescens dichloromethane
fraction was the most active, causing sublethal (growth inhibition) and lethal toxicity. Thus, this fraction was submitted
to another fractionation procedure resulting in three subfractions (dichloromethane, ethyl acetate and methanol) that were
tested against S. frugiperda caterpillars. All subfractions lead to significant sublethal effects, however, without significant
mortality. The chemical diversity in the subfractions of A. arborescens was assessed through untargeted approaches, such
as molecular networking and the in silico annotation tool NAP, by which two withanolides glycosides were annotated:
(22R)-1-Oxo-3beta-(beta-D-gluc... Mostrar Tudo |
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Palavras-Chave: |
Acnistus arborescens; Botanical insecticides; Chromatographic procedures; Datura stramonium; Fall armyworm; Withanolides. |
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Categoria do assunto: |
O Insetos e Entomologia |
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Marc: |
LEADER 02753naa a2200265 a 4500
001 1131469
005 2021-11-10
008 2021 bl uuuu u00u1 u #d
100 1 $aLIMA, A. F.
245 $aSearching for bioactive compounds from Solanaceae$blethal and sublethal toxicity to Spodoptera frugiperda and untargeted metabolomics approaches.$h[electronic resource]
260 $c2021
520 $aThe fall armyworm, Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae), is a major pest of maize crops and others row crops on the American continent, and this pest has spread to Africa and Asia. Such lepidopteran pest presents resistant populations to synthetic insecticides and to Bacillus thuringiensis (Bt) toxins and, consequently, new (bio) insecticides with distinct modes of action are required. In order to search for derivatives from Solanaceae as a potential source of bioactive compounds, a screening of 38 ethanolic extracts were prepared from 25 Solanaceae species. Using dietary exposure assessment, the ethanolic extracts from leaves of Acnistus arborescens (L.) Schltdl. and Datura stramonium L. were the most promising derivatives. A bioguided fractionation was performed with both plant species. The A. arborescens dichloromethane fraction was the most active, causing sublethal (growth inhibition) and lethal toxicity. Thus, this fraction was submitted to another fractionation procedure resulting in three subfractions (dichloromethane, ethyl acetate and methanol) that were tested against S. frugiperda caterpillars. All subfractions lead to significant sublethal effects, however, without significant mortality. The chemical diversity in the subfractions of A. arborescens was assessed through untargeted approaches, such as molecular networking and the in silico annotation tool NAP, by which two withanolides glycosides were annotated: (22R)-1-Oxo-3beta-(beta-D-glucopyranosyloxy)-14,20,22,27-tetrahydroxyergosta-5,24-diene-26-oic acid delta-lactone and withanoside XI. Therefore, derivatives of Solanaceae present promising compounds that may be useful in the framework of S. frugiperda integrated pest management. In addition, metabolomics is an innovative alternative and powerful approach to facilitate the putative identification of compounds in studies of natural products.
653 $aAcnistus arborescens
653 $aBotanical insecticides
653 $aChromatographic procedures
653 $aDatura stramonium
653 $aFall armyworm
653 $aWithanolides
700 1 $aRIBEIRO, L. P.
700 1 $aGONÇALVES, G. L. P.
700 1 $aMAIMONE, N. M.
700 1 $aGISSI, D. S.
700 1 $aLIRA, S. P.
700 1 $aVENDRAMIM, J. D.
773 $tJournal of Pest Science, Dordrecht, p. 1-13, 2021.
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Epagri-Sede (Epagri-Sede) |
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| Registros recuperados : 3 | |
| 1. |  | LORENZI, É. F. P.; LIMA, A. F.; PERUCH, L. A. M.; RACCA FILHO, F. Espécies de moscas-brancas em lavouras de mandioca no sul de Santa Catarina. In: CONGRESSO BRASILEIRO DE MANDIOCA, 16., CONGRESSO LATINO-AMERICANO E CARIBENHO DE MANDIOCA, 1., 2015, Foz do Iguaçu. Resumos... Botucatu: SBM, 2015.| Tipo: Resumo em Anais de Congresso |
| Biblioteca(s): Epagri-Sede. |
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| 2. | | LIMA, A. F.; RIBEIRO, L. P.; LIRA, S. P.; CARVALHO, G. A.; VENDRAMIM, J. D. Growth Inhibitory Activities and Feeding Deterrence of Solanaceae-Based Derivatives on Fall Armyworm. Agriculture, Basiléia, Suíça, v. 13, p. 1-11, 2023.| Tipo: Artigo em Periódico Indexado |
| Biblioteca(s): Epagri-Sede. |
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| 3. | | LIMA, A. F.; RIBEIRO, L. P.; GONÇALVES, G. L. P.; MAIMONE, N. M.; GISSI, D. S.; LIRA, S. P.; VENDRAMIM, J. D. Searching for bioactive compounds from Solanaceae: lethal and sublethal toxicity to Spodoptera frugiperda and untargeted metabolomics approaches. Journal of Pest Science, Dordrecht, p. 1-13, 2021.| Tipo: Artigo em Periódico Indexado | Circulação/Nível: Internacional - A |
| Biblioteca(s): Epagri-Sede. |
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| Registros recuperados : 3 | |
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